Inactivation of Influenza Virus by Caseinase C from Streptomyces albus G Culture-filtrate

The exoceliular , B - lactamase of Streptomyces albus G

The exoceilular f-lactamase of Streptomyces albus G has been purified to near protein homogeneity. It consists of one single polypeptide chain of mol.wt. 30000-31000, has a rather low isoelectric point (at pH 6.0) and contains less lysine (2.1%) and more half-cystine residues than most fi-lactamases from other Gram-positive bacteria. Penicillins are much better substrates than A3-cephalosporins...

Formation of 8-azaguanine from guanine by Streptomyces albus.

For many years, 8-azaguanine (1) has received much attention because of its remarkable biological activity''. In 1961, this compound was found to be a metabolite of Streptomyces albus var. pathocidicus and named pathocidin2'. The same strain also produces a cytosine nucleoside antibiotic, blasticidin S. Because it is an example of an unusual nucleobase occurring in nature, we became interested ...

The active sites of the beta-lactamases of Streptomyces cacaoi and Streptomyces albus G.

The active-site serine of the extracellular beta-lactamases of Streptomyces cacaoi and Streptomyces albus G has been labelled with beta-iodopenicillanate. The determination of the sequence of the labelled peptides obtained after trypsin digestion of the denatured proteins indicate both enzymes to be class A beta-lactamases. Surprisingly the two Streptomyces enzymes do not appear to be especiall...

Identification of streptococci: use of lysozyme and Streptomyces albus filtrate in the preparation of extracts for Lancefield grouping.

A combination of lysozyme and Streptomyces albus filtrate has been shown effective in extracting group-specific antigen for all commonly occurring serologically groupable streptococci. A prospective comparison of this method with that of Rantz and Randall (1955) for grouping 761 clinical isolates has confirmed its accuracy, which in our hands exceeded that of the latter more complicated method ...

C-17 epimers of deoxy-(O-8)-salinomycin from Streptomyces albus (ATCC 21838).